HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropiophenone → HCID 69203642, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropiophenone | HCID 16452 | — |
| Reactant | HCID 20437426 | HCID 20437426 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 69203642 | HCID 69203642 | 146.7% |
Reaction Steps
A mixture of N-(4-chlorobenzyl)piperazine dihydrochloride (5 g, 20 mmol), anhydrous KHCO3 (70 mmol) and 2-bromo-1-phenylpropan-1-one (3.96 ml, 26 mmol) in 40 ml of anhydrous ethanol was refluxed for 8 hours, and then treated according to general preparation 2 to give 6.1 g of compound (IV-2), yield 59.51%, mp 260-262° C. M+ 342.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332495B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-234f7227633c47a1abdb423179b67432 |
| Source note | uspto-grants-2008_02 |