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HRID2055220

反应详情

EQUATION

反应方程式

HRID 2055220 的结构方程式

REACTANTS

反应物

3
结构：O=C(CCl)c1ccccc1
HCID10757

2-Chloroacetophenone

C8H7ClO

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：Cl.Cl.O=[N+]([O-])c1ccc(CN2CCNCC2)cc1
HCID18005679

1-[(4-Nitrophenyl)methyl]piperazine--hydrogen chloride (1/2)

C11H17Cl2N3O2

PRODUCTS

生成物

1
结构：Cl.Cl.O=C(CN1CCN(Cc2ccc([N+](=O)[O-])cc2)CC1)c1ccccc1
HCID86606197

未命名化合物

收率 75%

PROCEDURE

实验过程

A mixture of N-(4-nitrobenzyl)piperazine dihydrochloride (10 g, 34 mmol), 2-chloro-1-phenylethanone (5.80 g, 37 mmol) and anhydrous K2CO3 (16.5 g, 119 mmol) was treated according to general preparation 2 to give 10.51 g of N1-(4-nitrobenzyl)-N4-phenacyl piperazine dihydrochloride (A), yield 75%, mp 236-8° C.

WORKUP

后处理

  1. additionwas treated
  2. customaccording to general preparation 2