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HRID2055223

反应详情

EQUATION

反应方程式

HRID 2055223 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)Nc1ccc(C(=O)CCl)cc1
HCID8805

4'-(Chloroacetyl)acetanilide

C10H10ClNO2

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：Cl.Cl.O=[N+]([O-])c1ccc(CN2CCNCC2)cc1
HCID18005679

1-[(4-Nitrophenyl)methyl]piperazine--hydrogen chloride (1/2)

C11H17Cl2N3O2

PRODUCTS

生成物

1
结构：CC(=O)Nc1ccc(C(=O)CN2CCN(Cc3ccc([N+](=O)[O-])cc3)CC2)cc1.Cl.Cl
HCID69055552

未命名化合物

收率 74%

PROCEDURE

实验过程

A mixture of N-(4-nitrobenzyl)piperazine dihydrochloride (2.94 g, 10 mmol), N-[4-(2-chloroacetyl)phenyl]acetamide (2.37 g, 12 mmol) and anhydrous K2CO3 (4.83 g, 35 mmol) was treated according to general preparation 2 to give compound (IV-18), yield 74%, mp 228-230° C. M+ 396.

WORKUP

后处理

  1. additionwas treated
  2. customaccording to general preparation 2
  3. customto give compound (IV-18), yield 74%, mp 228-230° C