HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86606199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(Bromomethyl)-1-methoxy-4-nitrobenzene | HCID 77516 | — |
| Reactant | 1-Phenyl-2-(piperazin-1-yl)ethan-1-one--hydrogen chloride (1/2) | HCID 23080512 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 86606199 | HCID 86606199 | 133.4% |
Reaction Steps
A mixture of N-phenacyl piperazine dihydrochloride (1.7 g, 6.1 mmol), 2-methoxy-5-nitro-benzylbromide (1.5 g, 6.1 mmol) and K2CO3 (2.7 g, 19.5 mmol) in 40 ml of acetone was treated according to general preparation 2 to give 1.80 g of compound (IV-23), yield 60%. M+ 368.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332495B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-6b61515ba681472cacebd3a4844ff10a |
| Source note | uspto-grants-2008_02 |