HRID2055226

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11430

Potassium Carbonate

CK2O3

HCID4961739

1-(1-chloroethyl)-4-fluorobenzene

C8H8ClF

HCID23080512

1-Phenyl-2-(piperazin-1-yl)ethan-1-one--hydrogen chloride (1/2)

C12H18Cl2N2O

PRODUCTS

生成物

结构：CC(c1ccc(F)cc1)N1CCN(CC(=O)c2ccccc2)CC1.Cl.Cl

HCID86606201

未命名化合物

收率 62.6%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A mixture of N-phenacyl piperazine dihydrochloride (1.39 g, 5 mmol), 1-(1-chloroethyl)-4-fluorobenzene (0.95 g, 6 mmol) and K2CO3 (2.42 g, 17.5 mmol) in 40 ml of acetone was treated according to general preparation 2 to give 1.25 g of compound (IV-24), yield 61%. M+ 326.

WORKUP

后处理

additionwas treated
customaccording to general preparation 2