HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → N1-Cinnamyl-N4-[1-(5-chloro-6-methoxy-2-naphthoyl)ethyl]piperazine dihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2-Bromo-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one | HCID 13699429 | — |
| Edukt | N-cinnamyl piperazine dihydrochloride | HCID 53411725 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | N1-Cinnamyl-N4-[1-(5-chloro-6-methoxy-2-naphthoyl)ethyl]piperazine dihydrochloride | HCID 69201459 | 437,1% |
Reaktionsschritte
A mixture of N-cinnamyl piperazine dihydrochloride (2.75 g, 10 mmol), 2-bromo-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one (1.05 g, 3.2 mmol) and K2CO3 (1.3 g, 9.5 mmol) in 50 ml of CHCl3 was treated according to general preparation 2 to give 3.65 g of compound (IV-35), yield 70%. M+ 449.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07332495B2 |
| Quelldatensatz | uspto-grants-2008_02 |
| ORD ID | ord-8cedec75ec614abca71637cf6c11a06f |
| Quellennotiz | uspto-grants-2008_02 |