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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2055479Generated: November 1, 2026

2-Chloro-1-(3-fluorophenyl)ethan-1-one → HCID 57978130, compound

https://huagongshe.com/reaction/2055479

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-(3-fluorophenyl)ethan-1-oneHCID 22248838—
Reactant5-bromo-1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 59657619—
ProductHCID 57978130HCID 57978130—

Reaction Steps

Following the general procedure III as described above, the alkylation of 5-bromo-1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one with commercially available 2-chloro-1-(3-fluoro-phenyl)-ethanone gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07332501B2
Source datasetuspto-grants-2008_02
ORD IDord-423df0dac86346ee989af81558786fd3
Source noteuspto-grants-2008_02