HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-3-Carboxylic Acid → 5-Bromo-1'-(1H-indol-3-ylcarbonyl)spiro[indole-3,4'-piperidin]-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-3-Carboxylic Acid | HCID 69867 | — |
| Reactant | 5-Bromospiro[indoline-3,4'-piperidin]-2-one | HCID 59657582 | — |
| Product | 5-Bromo-1'-(1H-indol-3-ylcarbonyl)spiro[indole-3,4'-piperidin]-2(1H)-one | HCID 59657612 | — |
Reaction Steps
Following the general procedure I as described above, the acylation of 5-bromospiro[indole-3,4′-piperidin]-2(1H)-one with 1H-indole-3-carboxylic acid (commercially available), gave the title compound. ES-MS m/e (%): 424.3(M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07332501B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-a7df51b296974957868782c620969a53 |
| Source note | uspto-grants-2008_02 |