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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2056748Generated: October 30, 2026

(1S)-1-(2-Hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-carboxamide → 1-(2-Hydroxyethyl)-1,3-dihydro-2-benzofuran-5-carboxamide

https://huagongshe.com/reaction/2056748

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S)-1-(2-Hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-carboxamideHCID 69308374—
Reactant1-(2-((Tert-butyldimethylsilyl)oxy)ethyl)-1,3-dihydroisobenzofuran-5-carboxamideHCID 69310172—
Product1-(2-Hydroxyethyl)-1,3-dihydro-2-benzofuran-5-carboxamideHCID 69307270—

Reaction Steps

Prepared from 1-[2-(tert-butyldimethylsilanoxy)-ethyl]-1,3-dihydro-2-benzofuran-5-carboxamide, as described for the preparation of (1S)-1-(2-hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07335660B2
Source datasetuspto-grants-2008_02
ORD IDord-c8d7a7aa83e84e0abfd8c89df0ffd219
Source noteuspto-grants-2008_02