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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2056753Generated: November 1, 2026

(2R)-4-(6-fluoro-1-naphthyl)-2-methylpiperazine → 1-(2-[(2R)-4-(6-Fluoro-1-naphthyl)-2-methyl-piperazinyl]ethyl}-3,4-dihydro-1H-2-benzopyran-6-carbonitrile

https://huagongshe.com/reaction/2056753

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-4-(6-fluoro-1-naphthyl)-2-methylpiperazineHCID 69307275—
Reactant2-(6-Cyano-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonateHCID 86596014—
Product1-(2-[(2R)-4-(6-Fluoro-1-naphthyl)-2-methyl-piperazinyl]ethyl}-3,4-dihydro-1H-2-benzopyran-6-carbonitrileHCID 69307318—

Reaction Steps

Prepared by condensation of 2-(6-cyano-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonate with (3R)-1-(6-Fluoro-1-naphthyl)-3-methylpiperazine, as described for Example 1b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07335660B2
Source datasetuspto-grants-2008_02
ORD IDord-fa4aadf3dc074eefa658b2abcafff9cb
Source noteuspto-grants-2008_02