HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 23249780, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 10856884 | HCID 10856884 | — |
| Reactant | HCID 13949662 | HCID 13949662 | — |
| Solvent | Hexane | HCID 8058 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 23249780 | HCID 23249780 | 86% |
Reaction Steps
Repeat Step (a) of EXAMPLE 1, but replace (2R,3S)-3-amino-4-methylpentan-2-ol with (1R,2S)-2-amino-3-methyl-1-phenylbutan-1-ol, and replace Na2CO3 (1.16 g, 11.0 mmol) with K2CO3 (1.52 g, 11.0 mmol). Column chromatography (Silica gel, eluent is n-Hexane:EtOAc=10:1) is used to purify the coarse product and a slightly-yellow liquid (1.00 g) is obtained. The yield is 86% and the other analysis includes:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07335781B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-1a29a8cf9fda42be91ac8898b736b392 |
| Source note | uspto-grants-2008_02 |