Trimethyl Phosphate → HCID 178502936, compound

HRID 2057148Notes

Reaction equation

HRID 2057148 reaction equation
[Cl-].[C:2]1([I+:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[P:15](OC)([O:19][CH3:20])([O:17][CH3:18])=[O:16]>>[CH3:18][O:17][PH:15](=[O:16])[O:19][CH3:20].[C:9]1([I+:8][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 10541Trimethyl PhosphateHCID 73870Diphenyliodonium chloride

Product 1

HCID 178502936HCID 178502936, compoundYield 81.6%

Procedure

Diphenyliodonium chloride (315 mg; 1 mmol) and trimethyl phosphate (1 g) were stirred at 170° C. for 10 minutes. After the reactants were dissolved, the mixture was cooled, to thereby yield solid matter. The solid matter was washed with ether, to thereby yield 250 mg of the target compound as white crystals (yield: 81.6%). The anion content of the resultant compound was determined by ion chromatography. The chloride anion content was determined to be not greater than 10 ppm.

Workup

  1. dissolutionAfter the reactants were dissolved
  2. temperaturethe mixture was cooled
  3. customto thereby yield solid matter
  4. washThe solid matter was washed with ether

Sources & evidence

ORD record
ord-c41bd97aa0c7481eb1a7ac029bbd5195
Source dataset
uspto-grants-2008_02
Patent number
US07335787B2

Reaction notes

Loading…