HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 1H,2H,3H,4H,5H,11H,11aH-[1,4]diazepino[1,2-a]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Azepindole | HCID 33471 | — |
| Reactant | Borane;tetrahydrofuran | HCID 2723981 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1H,2H,3H,4H,5H,11H,11aH-[1,4]diazepino[1,2-a]indole | HCID 12424660 | 75% |
Reaction Steps
In an operation carried out in a manner similar to that described in Example I but employing 22 grams of 2,3,4,5-tetrahydro-1H-[1,4]-diazepino[1,2-a]indole, milliliters of 1 M BH3.THF in tetrahydrofuran and milliliters of trifluoroacetic acid, a 75 percent yield of 2,3,4,5,11,11a-hexahydro-1H-[1,4]-diazepino[1,2-a]indole was obtained as determined by GLC on the isolated product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04210590 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-c7147503121f4138945336cc6beb9ab5 |
| Source note | uspto-grants-1980_07 |