Acetic Acid → Hydrochloric Acid

HRID 2057407Notes

Reaction equation

HRID 2057407 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([Cl:19])[C:5]2[O:10][CH2:9][CH2:8]C(C#N)(O[Si](C)(C)C)[C:6]=2[CH:18]=1.[C:20]([OH:23])(=[O:22])[CH3:21]>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([Cl:19])[C:5]2[O:10][CH2:9][CH2:8][CH:21]([C:20]([OH:23])=[O:22])[C:6]=2[CH:18]=1

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 13053012HCID 13053012, compound

Product 2

HCID 313Hydrochloric AcidHCID 13953800HCID 13953800, compound

Procedure

Following the procedure of Example 2, 6,8-dichloro-4-cyano-4-trimethylsilyloxy-3,4-dihydro-2H-1-benzopyran (3.0 g.) and stannous chloride dihydrate (15.0 g.) were reacted in glacial acetic acid (25 ml.) and concentrated hydrochloric acid (25 ml.) to form 6,8-dichloro-3,4-dihydro-2H-1-benzopyran-4-carboxylic acid. Recrystallization from cyclohexane yielded 1.33 g. of product, m.p. 124.5°-126° C.

Sources & evidence

ORD record
ord-33a0f824c5374d3b95e896ddbb233500
Source dataset
uspto-grants-1980_07
Patent number
US04210663

Reaction notes

Loading…