HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → HCID 23312291, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 23312335 | HCID 23312335 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23312291 | HCID 23312291 | — |
Reaction Steps
Analogously to Example 10, 8.0 g of 1-acetyl-4-(2-benzofuranyl)-piperidine in 100 ml of tetrahydrofuran is reduced with 12.0 g of lithium aluminium hydride in 150 ml of tetrahydrofuran, whereby the reaction mixture is refluxed for 15 hours. The crude 1-ethyl-4-(2-benzofuranyl)-piperidine obtained is converted into the hydrochloride which, after recrystallisation from ethyl acetate, melts at 198°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04210655 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-aa2eee4e95e54096993090db691ebfbc |
| Source note | uspto-grants-1980_07 |