HCID 20231523, compound → HCID 20286840, compound

HRID 2057444Notes

Reaction equation

NC(CCCCCCCCC(N)C(C)C)C(C)C.[CH:19]1([CH:27]2[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH:30]([CH:39]3[CH2:46][CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]3)[NH:29][NH:28]2)[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[NH2:28][CH:27]([CH:19]1[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]1)[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH:30]([NH2:29])[CH:39]1[CH2:46][CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]1

Participants

Reactant 2

HCID 20231523HCID 20231523, compound

HCID 20332297HCID 20332297, compound

Product 1

HCID 20286840HCID 20286840, compound

Procedure

The procedure described in (a) is repeated, starting from 65 g (0.168 mole) of 3,12-dicyclooctyl-1,2-diazacyclododecane and using correspondingly reduced amounts of catalyst and solvent, affording after purification by chromatography 43.6 g (66% of theory) of 1,10-diamino-1,10-dicyclooctyldecane as a colourless oil [nD20 =1.5050; IR spectrum (liquid) includes bands at 3333, 3278, 1613 cm-1 ].

Workup

customaffording
customafter purification by chromatography 43.6 g (66% of theory) of 1,10-diamino-1,10-dicyclooctyldecane as a colourless oil [nD20 =1.5050; IR spectrum (liquid) includes bands at 3333, 3278, 1613 cm-1 ]

Sources & evidence

ORD record: ord-a6f42d2f314b4e6b85e3f154b2662737
Source dataset: uspto-grants-1980_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04210742

Reaction notes

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