HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetylacetone → Ethanone, 1-(4-amino-2-methyl-5-(2-methylphenyl)-1H-pyrrol-3-yl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetylacetone | HCID 31261 | — |
| Reactant | α-Amino-2-methylbenzeneacetonitrile | HCID 16767703 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ethanone, 1-(4-amino-2-methyl-5-(2-methylphenyl)-1H-pyrrol-3-yl)- | HCID 41888 | — |
Reaction Steps
Starting from 2-amino-2-(o-tolyl)acetonitrile and acetylacetone, the open-chain intermediate compound is obtained, b.p. 120° C./0.2 mm Hg. The title compound is obtained in a 77% overall yield, m.p. 258° C. (from methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04211708 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-96cb8ea122b443bcb3a750f5f38d52a8 |
| Source note | uspto-grants-1980_07 |