Diethyl Ether → HCID 178503962, compound

HRID 2057624Notes

Reaction equation

HRID 2057624 reaction equation
[CH:1]1[C:13]2[CH:12]([NH:14][C:15]([NH2:17])=[S:16])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.C[I:19].[CH3:20]COCC>CC(C)=O>[IH:19].[CH:10]1[C:11]2[CH:12]([NH:14][C:15]([S:16][CH3:20])=[NH:17])[C:13]3[C:5](=[CH:4][CH:3]=[CH:2][CH:1]=3)[C:6]=2[CH:7]=[CH:8][CH:9]=1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 6328Methyl iodideHCID 20331562HCID 20331562, compound

Product 1

HCID 178503962HCID 178503962, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To 7.85 g. (0.033 mole) of N-(9-fluorenyl)thiourea in 200 ml acetone is added 4.68 g (0.033 mole) of methyl iodide. The mixture is allowed to stand at room temperature for about 4 hours. Ether (400 ml) is added and the mixture allowed to stand overnight, affording the crystalline product, methyl N-(9-fluorenyl)carbamimidothioate hydroiodide, which is filtered off; m.p. (208) 212°-14° C.

Workup

  1. waitto stand overnight

Sources & evidence

ORD record
ord-8d4f22b6387b46ebaa285bfdb5a68d6c
Source dataset
uspto-grants-1980_07
Patent number
US04211867

Reaction notes

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