反应详情

3.84 gm of 2,2,4-trimethyl-cyclopentanone were dissolved in 50 ml of chloroform and cooled in the ice bath. At 0° C., a solution of 0.2 gm of sodium acetate in 11.4 gm of a 40% aqueous peracetic acid was added. The reaction mixture was stirred for 18 hours at room temperature, then neutralized with a sodium hydrogen carbonate solution. The organic phase was separated, dried and concentrated. By distillation, 3.4 gm of 4,6,6-trimethyl-tetrahydropyran-2 -one (I) were recovered with the following characteristics:

1. customThe organic phase was separated
2. customdried
3. concentrationconcentrated
4. distillationBy distillation, 3.4 gm of 4,6,6-trimethyl-tetrahydropyran-2 -one (I)
5. customwere recovered with the following characteristics