HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → H-Thr(But)-Ser(But)-OH.HCl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Z-Thr(But)-Ser(But)OH | HCID 129820266 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | H-Thr(But)-Ser(But)-OH.HCl | HCID 131711820 | — |
Reaction Steps
25 g (55.24 mmoles) of Z-Thr(But)-Ser(But)-OH are dissolved in 200 ml of methanol and are hydrogenated catalytically (at pH 4.5) using an autotitrator, with addition of a solution of HCl in methanol. After completion of the hydrogenation, the Pd/BaSO4 catalyst is filtered off, the filtrate is concentrated and the residue is dried in a high vacuum. Yield 1.1 g of an amorphous product
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04212796 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-5202ccddff8844388f38367cc7dcc128 |
| Source note | uspto-grants-1980_07 |