HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-Nitrosooctahydro-2H-pyrido[1,2-a]pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Sodium Nitrate | HCID 24268 | — |
| Reactant | (+-)-1,4-Diazabicyclo[4.4.0]decane | HCID 2876391 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Nitrosooctahydro-2H-pyrido[1,2-a]pyrazine | HCID 45099493 | — |
Reaction Steps
Octahydropyrido-[1,2-a]-pyrazine (5 g) was dissolved in hydrochloric acid (5 N, 16 ml) and sodium nitrate (2.7 g) in water (10 ml) added dropwise at 0°. The solution was then heated at 60° for 30 minutes and stood at room temperature for 3 hours. It was basified, saturated with potassium carbonate and extracted with ether. The ethereal extract was dried and evaporated to give N-nitroso-octahydropyrido-[1,2-a]-pyrazine as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04213983 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-efceddec38164246b24abb76587a7529 |
| Source note | uspto-grants-1980_07 |