反应详情

A solution of 11-(3-chloropropionyl)-5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one in dioxane was refluxed for one hour in the presence of an excess of triethylamine to obtain a good yield of 11-(acryloyl)-5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one which after crystallization from acetonitrile melted at 235° C. with decomposition.