HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one → 11-(4-chlorobutyryl)-5,11-dihydro-6H-pyrido [2,3-b][1,4]-benzodiazepin-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one | HCID 70169 | — |
| Reactant | 4-Chlorobutyryl chloride | HCID 78370 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 11-(4-chlorobutyryl)-5,11-dihydro-6H-pyrido [2,3-b][1,4]-benzodiazepin-6-one | HCID 15925617 | — |
Reaction Steps
A solution of 4-chlorobutyryl chloride and 5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one in xylene was reacted to obtain 11-(4-chlorobutyryl)-5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one which after crystallization from ethyl acetate melted at 205°-207° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04213985 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-cc6d7efbf6754777a00bf08387fb5a8e |
| Source note | uspto-grants-1980_07 |