HuagongsheHuagongshe Chemistry Print Report · For research reference only
11-(3-chloropropionyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one → HCID 86737102, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 11-(3-chloropropionyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 13810571 | — |
| Reactant | HCID 86737104 | HCID 86737104 | — |
| Product | HCID 86737102 | HCID 86737102 | 62% |
Reaction Steps
Using the procedure of Example 7, 11-(3-chloropropionyl)-5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one was reacted with 1-phytyl-piperazine to obtain a 62% yield of 5,11-dihydro-11-[3-(4-phytyl-1-piperazinyl)-propionyl]-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one dihydrochloride which melted at 204°-210° C. (with decomposition) after crystallization from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04213985 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-0de5e6c4d17c4b8897d1012d95cc1c87 |
| Source note | uspto-grants-1980_07 |