HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one → 11-(6-chlorocaproyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one | HCID 70169 | — |
| Reactant | 6-Chlorohexanoyl chloride | HCID 88014 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 11-(6-chlorocaproyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 15924302 | — |
Reaction Steps
A solution of 5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one and 6-chloro-caproyl chloride in xylene was reacted to obtain 11-(6-chloro-caproyl)-5,11-dihydro-6H-pyrido-[2,3-b][1,4]-benzodiazepine-6-one melting at 128°-130° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04213985 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-004e6a4c734f4951aab5e939b95627e5 |
| Source note | uspto-grants-1980_07 |