HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → HCID 20329345, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Methanesulfonate | HCID 85257 | — |
| Reactant | HCID 20329310 | HCID 20329310 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20329345 | HCID 20329345 | — |
Reaction Steps
3.35 g of 1-(Hydroxymethyl)-8-chloro-6-phenyl-4H-s-triazolo[4,3-a][1,5]benzodiazepin-5-one, methanesulfonate in 15 ml dimethylsulfoxide at 0° is added dropwise with stirring to 3 ml of diethylamine in 10 ml dimethylsulfoxide. The reaction is stirred at 20° for 2 hours, diluted with methylene chloride, washed with water and then saturated aqueous sodium chloride. After drying, the solvent is evaporated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04213982 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-6e0d82dc35b34ca8a7d4e451861235f8 |
| Source note | uspto-grants-1980_07 |