HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)acetyl)-5-methyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Piperonylpiperazine | HCID 94426 | — |
| Reactant | 11-(2-Chloroacetyl)-5,11-dihydro-5-methyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 20329370 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)acetyl)-5-methyl- | HCID 3053220 | — |
Reaction Steps
10.5 gm of 11-chloroacetyl-5,11-dihydro-5-methyl-6H-pyrido[2,3-b]-[1,4]benzodiazepine-6-one, 3.8 gm of sodium carbonate and 8 gm of 1-[(3,4-methylenedioxy)benzyl]-piperazine were reacted in 200 ml of absolute ethanol and worked up in analogy to Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04213984 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-b35f5fbf835540988478dcd690f9f8ff |
| Source note | uspto-grants-1980_07 |