HCID 20329788, compound → HCID 20329773, compound

Participants

Reaction Steps

A 0.8-g portion of the p-methoxyphenyl 7-nitro-1,2,3,4-tetrahydro-1-naphthoate obtained above was catalytically reduced with 5% palladium-carbon in acetic acid. After removal of the catalyst by filtration, the acetic acid was removed by distillation under reduced pressure to obtain p-methoxyphenyl 7-amino-1,2,3,4-tetrahydro-1-naphthoate, which was then dissolved in diethyl ether, and dry gaseous hydrogen chloride was introduced into the resulting solution to obtain 520 mg of p-methoxyphenyl 7-amino-1,2,3,4-tetrahydro-1-naphthoate hydrochloride, m.p. 155°-156° C.

Provenance & Evidence