Sodium Hydroxide → HCID 54716191, compound

Participants

Reaction Steps

A stirred mixture of 0.5 g. of 1-ethyl-1,2-dihydro-4-hydroxy-7-methyl-2-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester was heated under reflux for 5 hours in 20 ml. of a 20% sodium hydroxide solution was cooled and was acidified with glacial acetic acid. The precipitate which formed was collected, air dried and was recrystallized from ethanol to give 0.2 g. of the title compound, m.p. 320°-3° C. dec.

Provenance & Evidence