HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichlorobenzyl chloride → 1-[3-(3,4-Dichloroanilino)-2-(2,4-dichlorobenzyloxy)propyl]-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichlorobenzyl chloride | HCID 7212 | — |
| Reactant | 1-[3-(3,4-Dichloroanilino)-2-hydroxypropyl]imidazole | HCID 23350200 | — |
| Product | 1-[3-(3,4-Dichloroanilino)-2-(2,4-dichlorobenzyloxy)propyl]-imidazole | HCID 23350194 | — |
Reaction Steps
Reaction of 1-[3-(3,4-dichloroanilino)-2-hydroxypropyl]-imidazole with 2,4-dichlorobenzyl chloride yields 1-[3-(3,4-dichloroanilino)-2-(2,4-dichlorobenzyloxy)propyl]-imidazole. The base, purified by recrystallization from isopropanol, melts at 116°-117° C.; the methanesulfonate salt melts at 141°-143° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04215220 |
| Source dataset | uspto-grants-1980_07 |
| ORD ID | ord-15d20438b9b74395849488b666f5b136 |
| Source note | uspto-grants-1980_07 |