Hydrochloric Acid → 5-Biphenyl-4-yl-3-hydroxy-2-methyl-pentanoic acid tert-butyl ester
Reaction equation
[BH4-:1].[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8]([CH:9]([C:10]([CH2:11][CH2:12][c:13]1[cH:14][cH:15][c:16](-[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:17][cH:18]1)=[O:25])[CH3:26])=[O:27].[CH3:29][OH:30].[ClH:28].[Na+:2]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8]([CH:9]([CH:10]([CH2:11][CH2:12][c:13]1[cH:14][cH:15][c:16](-[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:17][cH:18]1)[OH:25])[CH3:26])=[O:27]Participants
6
Sources & evidence
- ORD record
- ord-0f8376dcd91e4d18874c3aa6293709a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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