HCID 12837422, compound → HCID 86738275, compound

HRID 2058440Notes

Reaction equation

HRID 2058440 reaction equation
[N+:1](=[C:3]1[C:20](=[O:21])[CH2:19][CH2:18][C@@:17]2([CH3:22])[C@H:4]1[CH2:5][CH2:6][C@@H:7]1[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]1[CH2:9][CH2:10][C@@H:11]2[OH:23])=[N-:2].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>>[N+:1](=[C:3]1[C:20](=[O:21])[CH2:19][CH2:18][C@@:17]2([CH3:22])[C@H:4]1[CH2:5][CH2:6][C@@H:7]1[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]1[CH2:9][CH2:10][C:11]2=[O:23])=[N-:2]

Participants

3

Reactant 2

HCID 12837422HCID 12837422, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 86738275HCID 86738275, compound

Procedure

4-Diazo-17β-hydroxymethyl-5αandrostan-3-one is oxidized with pyridinium chlorochromate according to the procedure described in Example 4 to give 4-diazo-3-oxo-5α-androstane-17β-carboxaldehyde. In a similar manner, 4-diazo-17β-hydroxy-5α-androstan-3-one is oxidized with pyridinium chlorochromate to give 4-diazo-5α-androstane-3,17-dione.

Sources & evidence

ORD record
ord-8074ad248aa44f82a7b894e592e281fa
Source dataset
uspto-grants-1982_03
Patent number
US04317817

Reaction notes

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