2-Methyl-2-thiopseudourea → HCID 140335238, compound

HRID 2058651Notes

Reaction equation

HRID 2058651 reaction equation
[CH3:1][S:2][C:3](=[NH:5])[NH2:4].[Cl:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[C:8]=1[CH:14]([Br:18])[C:15](Br)=[O:16]>CC(C)=O>[CH3:1][S:2][C:3](=[NH:4])[NH:5][C:15](=[O:16])[CH:14]([C:8]1[C:9]([Cl:13])=[CH:10][CH:11]=[CH:12][C:7]=1[Cl:6])[Br:18]

Participants

4

Reactant 2

HCID 51422-Methyl-2-thiopseudoureaHCID 20549424HCID 20549424, compound

Product 1

HCID 140335238HCID 140335238, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Conditions

Temperature
10 °C

Procedure

To 7 g S-methylisothiourea in 50 ml of acetone at 10 degrees C., there are added in drops 12 g of 2-(2,6-dichlorophenyl)-2-bromo-acetyl bromide in 30 ml acetone. The mixture is stirred for 30 minutes at 10 degrees C., and the precipitate is suction-filtered. After concentration of the mother liquor, a second fraction of S-methyl-N-[2-(2,6-dichlorophenyl)-2-bromo acetyl] isothiourea is obtained. The decomposition point is 177 degrees.

Workup

  1. customat 10 degrees C
  2. filtration, and the precipitate is suction-filtered

Sources & evidence

ORD record
ord-df4650ce70d3411b8f839c5bd6f8b53e
Source dataset
uspto-grants-1982_03
Patent number
US04318915

Reaction notes

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