反应详情

To a stirred suspension of 1.6 g. of the benzoxazole intermediate product of Example 1 in 50 ml. of glacial acetic acid is added 1.5 g. of 2-carboxybenzaldehyde. After a few minutes the mixture becomes homogeneous, then quickly thickens as a new precipitate forms. Stirring is continued for 16 hours, water is added, and the solid is filtered, washed with water and dried to give 2.5 g. of product, m.p. 253°-5°.

1. additionTo a stirred suspension of 1.6 g
2. waitAfter a few minutes the mixture becomes homogeneous
3. filtrationthe solid is filtered
4. washwashed with water
5. customdried
6. customto give 2.5 g