Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Morpholine, acetate | HCID 11964105 | — |
| Reactant | Sodium 3-hydroxyacrylonitrile | HCID 86738287 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 70548340 | HCID 70548340 | 75.4% |
Reaction Steps
30.3 g (0.25 mol) of sodium-3-hydroxyacrylonitrile (content 75%) is added to a solution of morpholine acetate (prepared from 26.1 g (0.3 mol) of morpholine and 18 g (0.3 mol) of acetic acid) in 200 ml of acetonitrile and is heated for 8 h at 65° C. After working up as in Example 55, 26.0 g (75.4%) of 3-morpholine acrylonitrile was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04319024 |
|---|
| Source dataset | uspto-grants-1982_03 |
|---|
| ORD ID | ord-c6eaf038b41046baa922de5942057c08 |
|---|
| Source note | uspto-grants-1982_03 |
|---|
