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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 205881Generated: October 26, 2026

1,4-Dioxane → 1-(3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)phenyl)urea

https://huagongshe.com/reaction/205881

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
Reactant1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
Reactant3-cyclopropyl-1-methyl-1H-pyrazol-5-amineHCID 2735311—
Reactantprop-1-en-2-yl 2-fluoro-4-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)phenylcarbamateHCID 66729122—
Product1-(3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)phenyl)ureaHCID 66728938—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-76c991cada7a4f66b1682d8b58647878
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)