1,4-Dioxane → 1-(3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)phenyl)urea
Reaction equation
[CH2:38]1[CH2:39][CH2:40][C:41]2=[N:46][CH2:45][CH2:44][CH2:43][N:42]2[CH2:47][CH2:48]1.[CH:1]1([c:4]2[n:5][n:6]([CH3:10])[c:7]([NH2:9])[cH:8]2)[CH2:2][CH2:3]1.[F:11][c:12]1[c:13]([NH:31][C:32]([O:33][C:35]([CH3:36])=[CH2:37])=[O:34])[cH:14][cH:15][c:16]([O:18][c:19]2[cH:20][c:21](-[c:25]3[cH:26][n:27][n:28]([CH3:30])[cH:29]3)[n:22][cH:23][cH:24]2)[cH:17]1.[O:49]1[CH2:50][CH2:51][O:52][CH2:53][CH2:54]1>>[CH:1]1([c:4]2[n:5][n:6]([CH3:10])[c:7]([NH:9][C:32]([NH:31][c:13]3[c:12]([F:11])[cH:17][c:16]([O:18][c:19]4[cH:20][c:21](-[c:25]5[cH:26][n:27][n:28]([CH3:30])[cH:29]5)[n:22][cH:23][cH:24]4)[cH:15][cH:14]3)=[O:33])[cH:8]2)[CH2:2][CH2:3]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-76c991cada7a4f66b1682d8b58647878
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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