Benzylaniline → HCID 13037485, compound

HRID 2058884Notes

Reaction equation

HRID 2058884 reaction equation
[CH2:1]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:15]1([P:21](Cl)(Cl)=[O:22])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[CH:15]1([P:21]2(=[O:22])[C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[CH2:1][N:8]2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 66028BenzylanilineHCID 2734036HCID 2734036, compound

Product 1

HCID 13037485HCID 13037485, compoundYield 14.5%

Procedure

The procedure of Example 1 was employed utilizing N-benzylaniline and cyclohexyl phosphonic dichloride. The crude product produced as a result of the chromatographic separation yielded without additional purification 1-cyclohexyl-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (2.7 g, 14.5% yield) as a beige solid having a melting point of 167°-169° C. and the following analysis:

Workup

  1. customThe crude product produced as
  2. customa result of the chromatographic separation

Sources & evidence

ORD record
ord-f3b877a608ae4d9ca86d336cdbaa71e5
Source dataset
uspto-grants-1982_03
Patent number
US04319913

Reaction notes

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