Benzylaniline → HCID 13037495, compound

HRID 2058894Notes

Reaction equation

HRID 2058894 reaction equation
[CH2:1]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[P:22](Cl)(Cl)=[O:23]>>[CH3:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[P:22]1(=[O:23])[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH2:1][N:8]1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 66028BenzylanilineHCID 10921725Phosphonic dichloride, (2-methylphenyl)-2×

Product 1

HCID 13037495HCID 13037495, compoundYield 8%

Procedure

The procedure of Example 1 was employed utilizing N-benzylaniline and 2-methylphenyl phosphonic dichloride. The reaction of the dilithio compound and the 2-methylphenyl phosphonic dichloride was conducted at 0° C. to yield 1-(2-methylphenyl)-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (0.8 g, 8% yield) as a yellow solid having a melting point of 181°-183° C. and the following analysis:

Workup

  1. customwas conducted at 0° C.

Sources & evidence

ORD record
ord-566fa30f635046999e9165701f1e645b
Source dataset
uspto-grants-1982_03
Patent number
US04319913

Reaction notes

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