N-(1,1-Dimethylethyl)benzenemethanamine → 1-isopropyl-2-t-butyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide

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Reaction Steps

The procedure of Example 30 was employed utilizing N-t-butyl-N-benzylamine and isopropyl phosphonic dichloride. The reaction of the dilithio compound and the isopropyl phosphonic dichloride was conducted at -70° C. The crude product produced as a result of the chromatographic separation was distilled at 130° C. and 0.1 mm to yield a colorless oil. The colorless oil was slurried in petroleum ether to yield 1-isopropyl-2-t-butyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (5.8 g, 39% yield) having a melting point of 67°-70° C. and the following analysis:

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