Isopropylbenzylamine → HCID 13037511, compound

Participants

Reaction Steps

The procedure of Example 30 was employed utilizing N-isopropyl-N-benzylamine and isopropyl phosphonic dichloride. The reaction of the dilithio compound and the isopropyl phosphonic dichloride was conducted at -70° C. The crude product produced as a result of the chromatographic separation was distilled at 130° C. and 0.1 mm to yield a colorless oil. This oil was slurried in petroleum ether to yield 1,2-diisopropyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (2.28 g, 16% yield) as a pale yellow oil having the following analysis:

Provenance & Evidence