Benzylaniline → HCID 13037519, compound

HRID 2058918Notes

Reaction equation

HRID 2058918 reaction equation
[CH2:1]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:15][C:16]([F:28])([F:27])[C:17]1[CH:22]=[CH:21][C:20]([P:23](Cl)(Cl)=[O:24])=[CH:19][CH:18]=1>>[F:28][C:16]([F:15])([F:27])[C:17]1[CH:22]=[CH:21][C:20]([P:23]2(=[O:24])[C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[CH2:1][N:8]2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 66028BenzylanilineHCID 12670629HCID 12670629, compound

Product 1

HCID 13037519HCID 13037519, compoundYield 4%

Procedure

The procedure of Example 38 was employed utilizing N-benzylaniline and 4-trifluoromethylphenyl phosphonic dichloride. The crude product produced as a result of the chromatographic separation was crystallized from diethyl ether and petroleum ether and recrystallized from diethyl ether to yield 1-[4-(trifluoromethyl)phenyl]-2-phenyl-2,3-dihydro-1H-2,1-benzazaphosphole-1-oxide (0.5 g, 4% yield) having a melting point of 187°-189° C.

Workup

  1. customThe crude product produced as
  2. customa result of the chromatographic separation
  3. customwas crystallized from diethyl ether and petroleum ether
  4. customrecrystallized from diethyl ether

Sources & evidence

ORD record
ord-c8a6001e2b4e486bbe9b72442fc26a7d
Source dataset
uspto-grants-1982_03
Patent number
US04319913

Reaction notes

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