Sulfuric Acid → HCID 22497902, compound

HRID 2058983Notes

Reaction equation

HRID 2058983 reaction equation
[C:1]1([CH:7]([C:9]2[CH:10]=[C:11]3[C:16](=[CH:17][CH:18]=2)[CH:15]=[C:14]([OH:19])[CH:13]=[CH:12]3)[CH3:8])[CH:6]=[CH:5][CH:4]=CC=1.C1C2C(=CC=CC=2)C=CC=1O.C=CC1C=CC=CC=1.S(=O)(=O)(O)O>>[CH:7]1([C:9]2[CH:18]=[C:17]3[C:12](=[CH:11][CH:10]=2)[CH:13]=[C:14]([OH:19])[CH:15]=[CH:16]3)[CH2:8][CH2:4][CH2:5][CH2:6][CH2:1]1

Participants

5

Reactant 4

HCID 1118Sulfuric AcidHCID 7501StyreneHCID 86632-NaphtholHCID 12182141HCID 12182141, compound

Product 1

HCID 22497902HCID 22497902, compound

Procedure

It is known that as a rule the alkylation of 2-naphthol with an olefin or alcohol in the presence of an inorganic acid or organic sulfonic acid principally gives a 6-alkylated 2-naphthol. J. Org. Che., 17 (1952), 243- 248 describes the preparation of 6-(α-phenylethyl)-2-naphthol by reacting 2-naphthol with styrene in the presence of sulfuric acid, the yield being 92 percent. J. Org. Chem., 16 (1951), 185-191 discloses that 6-cyclohexyl-2-naphthol is formed by reacting 2-naphthol with cyclohexanol in the presence of phosphoric acid.

Sources & evidence

ORD record
ord-e8a6a7232c1849e7af51197c8c38fce9
Source dataset
uspto-grants-1982_03
Patent number
US04320235

Reaction notes

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