Potassium Carbonate → HCID 11500273, compound

HRID 2059041Notes

Reaction equation

HRID 2059041 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11]2([CH2:16][N:17]3[CH:21]=[CH:20][N:19]=[CH:18]3)[O:15][CH2:14][CH2:13][O:12]2)=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+]>ClCCl>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11]2([CH2:16][N:17]3[CH:21]=[CH:20][N:19]=[CH:18]3)[O:12][CH2:13][CH2:14][O:15]2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 11659928HCID 11659928, compound

Product 1

HCID 11500273HCID 11500273, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1-[[2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl]methyl]imidazole hydrochloride (800 mg) in 50 ml of dichloromethane is shaken with excess dilute potassium carbonate solution until the salt is completely neutralized. The organic layer is then separated, washed twice with water, dried over magnesium sulfate and evaporated to yield 1-[[2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl]methyl]imidazole.

Workup

  1. customThe organic layer is then separated
  2. washwashed twice with water
  3. dry with materialdried over magnesium sulfate
  4. customevaporated

Sources & evidence

ORD record
ord-cc3dfd7cbf184cf794935a296e20d960
Source dataset
uspto-grants-1982_03
Patent number
US04321272

Reaction notes

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