HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20545851, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 15587240 | HCID 15587240 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20545851 | HCID 20545851 | — |
Reaction Steps
One proceeds as described in Example 18 with the difference that 2-acetonyl-4,5-dimethoxy-2'-chlorobenzopnenone is applied as starting substance. The resulting crude 1-(2-chlorophenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine is treated with absolute ethanol containing hydrochloric acid to obtain the pure hydrochloride. [C18H18ClN2O2 ]Cl=365.5. The title compound decomposes at 186°-188° C. after recrystallization from absolute ethanol and ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04322346 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-58e2487682c241309611dff946d0f32b |
| Source note | uspto-grants-1982_03 |