HRID2059168

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15158

Ethyl dichlorophosphate

C2H5Cl2O2P

结构：CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

HCID10156152

Hydroxyprogesterone acetate

C23H32O4

PRODUCTS

生成物

结构：C=C1C[C@@H]2[C@H](CC[C@@]3(C)[C@H]2CC[C@]3(OC(C)=O)C(C)=O)[C@@]2(C)CCC(=O)C=C12

HCID94436

未命名化合物

PROCEDURE

实验过程

Analogously to Example 42, 1.0 g of 17α-acetoxy-4-pregnene-3,20-dione is reacted with 3.8 ml of ethyldichlorophosphate and worked up, thus obtaining 510 mg of 17α-acetoxy-6-methylene-4-pregnene-3,20-dione, mp 231°-233° C.