HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl dichlorophosphate → 17-hydroxy-6-methylenepregn-4-ene-3,20-dione 17-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl dichlorophosphate | HCID 15158 | — |
| Reactant | Hydroxyprogesterone acetate | HCID 10156152 | — |
| Product | 17-hydroxy-6-methylenepregn-4-ene-3,20-dione 17-acetate | HCID 94436 | — |
Reaction Steps
Analogously to Example 42, 1.0 g of 17α-acetoxy-4-pregnene-3,20-dione is reacted with 3.8 ml of ethyldichlorophosphate and worked up, thus obtaining 510 mg of 17α-acetoxy-6-methylene-4-pregnene-3,20-dione, mp 231°-233° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04322349 |
| Source dataset | uspto-grants-1982_03 |
| ORD ID | ord-c8a6ba6b83f74c4eac49cc539efe833a |
| Source note | uspto-grants-1982_03 |