Hydrochloric Acid → HCID 86738313, compound

Participants

Reaction Steps

To a solution of 2,3-dihydro-7-methyl-9-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-5H-1,4-thiazino[2,3,4-ij]-quinolin-5-one in dry pyridine can be added acetyl chloride. The solution is heated at reflux, and when the reaction is complete, the solution can be poured into cold 1 N hydrochloric acid solution, extracted, isolated and purified to give 2,3-dihydro-7-methyl-9-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-5H-1,4-thiazino-[2,3,4-ij]-quinolin-5-one acetate.

Provenance & Evidence