反应详情

3-Aminobenzisoxazole (2 gram), 2,6-dichlorobenzoylchloride (2 gram), and 50 ml. of toluene are heated at reflux for 16 hours. After evaporation of the solvent at reduced pressure, the resultant oily semi-solid is triturated with ether. The solid so formed is then washed with ether and water and constitutes the desired product.

1. temperatureat reflux for 16 hours
2. customAfter evaporation of the solvent at reduced pressure
3. customthe resultant oily semi-solid is triturated with ether
4. customThe solid so formed
5. washis then washed with ether and water