Mandelic Acid → HCID 13035114, compound

HRID 2059341Notes

Reaction equation

HRID 2059341 reaction equation
C(O)(=O)C(C1C=CC=CC=1)O.Cl.COC(=O)CNC1C=CC=CC=1.Cl.C(OC(=O)CNC1C=CC=CC=1)(C)C.[CH2:40]([O:50][C:51](=[O:60])[CH2:52][NH:53][C:54]1[CH:59]=[CH:58][CH:57]=[CH:56][CH:55]=1)[CH2:41][CH2:42][CH2:43]CCCCCC>>[CH2:40]([O:50][C:51](=[O:60])[CH2:52][NH:53][C:54]1[CH:55]=[CH:56][CH:57]=[CH:58][CH:59]=1)[CH2:41][CH2:42][CH3:43]

Participants

5

Reactant 4

HCID 1292Mandelic AcidHCID 12241365Methyl 2-(phenylamino)acetate hydrochlorideHCID 13035117HCID 13035117, compoundHCID 13035118HCID 13035118, compound

Product 1

HCID 13035114HCID 13035114, compound

Procedure

Using the method of Example 1, racemic mandelic acid was resolved in separate experiments with D(-) phenylglycine methyl ester HCl, D(-) phenylglycine isopropylester HCl, and D(-) phenylglycine decyl ester DCl. The following table gives the results of these experiments (compared with phenylglycine butyl ester):

Workup

  1. customThe following table gives the

Sources & evidence

ORD record
ord-5ca335d55e7d4b8296850bcfa6d681fb
Source dataset
uspto-grants-1982_03
Patent number
US04322548

Reaction notes

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